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Topamax is the brand name of topiramate, an anticonvulsant drug used to prevent seizures and reduce the frequency of migraines.
While its exact mechanism of action is unknown, studies suggest Topamax might alter the production or action of neurotransmitters in the brain, suppressing the abnormal activity of the nerves in the brain that cause seizures or preventing the abnormal activity from spreading to other nerves.
Other research has suggested that it might suppress the nerves directly, thereby making them less likely to fire.
The Food and Drug Administration (FDA) approved Topamax to treat seizures in 1996.
In 2004, Topamax received FDA approval for the prevention of migraines.
Manufactured by Janssen Pharmaceuticals, Topamax is now the number-one prescribed medication for migraine prevention in the United States.
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