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Glipizide is a prescription medication used to treat type 2 diabetes. Glipizide belongs to a group of drugs called sulfonylureas, which help lower blood sugar levels by causing the pancreas to secrete insulin.
This medication comes in regular tablet and extended release tablet forms. The regular tablet is taken one or more times a day before meals. The extended-release tablet is taken once a day with breakfast.
Common side effects of glipizide include nausea, diarrhea, and gas. Glipizide can cause dizziness. Do not drive or operate machinery until you know how glipizide affects you.  
G6PD is an enzyme in your body that is responsible for helping red blood cells to work properly. Some patients are born with less of this enzyme in their bodies, leading to the destruction of red blood cells. When glipizide is used in patients with G6PD deficiency, they have a higher chance of experiencing hemolytic anemia (a condition in which the body does not have enough red blood cells to deliver oxygen to your tissues).
G6PD testing may be done to determine whether you are at a higher risk of experiencing hemolytic anemia if you are to be treated with glipizide. 
Glipizide is a prescription medication used to treat type 2 diabetes. Glipizide lowers blood sugar levels along with exercise and an appropriate diet.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Glipizide may be found in some form under the following brand names:
Glipizide is part of the drug class:
Serious side effects have been reported with glipizide. See “Drug Precautions” section.
Common side effects of glipizide include:
This is not a complete list of glipizide side effects. Ask your doctor or pharmacist for more information.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
This is not a complete list of glipizide drug interactions. Ask your doctor or pharmacist for more information.
Serious side effects have been reported with glipizide including:
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of glipizide, there are no specific foods that you must exclude from your diet when receiving glipizide.
Alcohol can intensify the side effects of glipizide. Glipizide should be taken with a healthy diet to maximize its blood glucose lowering effects.
Before taking glipizide, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories – A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
Glipizide falls into category C. Studies in animals have shown a harmful and undesired effect on the unborn baby, yet there are no adequate and well-controlled studies in pregnant women.
Tell your doctor if you are breastfeeding or plan to breastfeed.
You should not take glipizide if you are breastfeeding. It may be excreted in your breast milk and may harm your nursing child.
Take glipizide exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
The dosage range for regular glipizide tablets is between 2.5 and 40 mg each day.  The maximum once daily dose is 15 mg.  Amounts above 15 mg per day should be split into different doses throughout the day.  The maximum daily dose is 40 mg.
The dosage range for extended-release glipizide tablets is 5 to 20 mg in one dose each day.  The maximum daily dose is 20 mg.
If you take too much glipizide, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

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